Glossary

PCT

Post-Cycle Therapy — a protocol used after a cycle of compounds that suppress endogenous hormone production, aimed at restoring natural hormonal function.

Also known as: Post-Cycle Therapy post cycle therapy

PCT is primarily relevant when using compounds that suppress the hypothalamic-pituitary-gonadal (HPG) axis — most commonly anabolic steroids and SARMs. After these compounds are discontinued, the body’s natural testosterone production may be suppressed, requiring PCT drugs (typically SERMs like Nolvadex or Clomid) to stimulate recovery.

Most peptides do not suppress endogenous hormone production and therefore do not require PCT. GHRPs and GHRHs stimulate the pituitary to release GH naturally and do not affect the HPG axis. PCT becomes relevant when peptide protocols are combined with SARMs or other androgens.

Related Terms